Knowledge for all

Importance of Semi-Conservative Replication There are two chains in the DNA and the two are complementary; when the chain replicated form the other chain, is known as semiconservative replication of DNA. The importance of DNA replication semi-conservative is to make two copies, each containing one of the original chains and a new chain synthesized. As you can see, the DNA is less organized during cell division, which is due to the chromosomes, which are not always present at the moment of cell division.

Inheritance Pattern of Sickle cell anaemia Sickle cell anaemia is an inherited disease. Two genes for sickle cell haemoglobin must be inherited from parents to have the disease. The genes involved in sickle cell disease control the production of a protein in red blood cells called haemoglobin. The haemoglobin binds to oxygen in the lungs and releases it to the peripheral tissues such as the liver and muscles. Most people have two normal genes for haemoglobin. Some people carry one normal gene and one gene for sickle cell haemoglobin. Below, the figure represents the anaemic state of haemoglobin genes inherited from parents with sickle cell trait and character of haemoglobin C. As indicated above, the couple has four possibilities for the child to have the genes for haemoglobin and sickle cell haemoglobin. C. The child would have a Haemoglobin SC disease. The Haemoglobin SC disease is usually milder than sickle cell disease. Unfortunately, some patients have a clinical course indisti...